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Index > Protein center > KIR2DL2(Gene name) > Human
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  • KIR2DL2 (Gene name),
  • Killer cell immunoglobulin-like receptor 2DL2 (Protein name ),  KI2L2_HUMAN from NCBI database.
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  • General Annotation
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  • Gene name:
    KIR2DL2(CD158B1;NKAT6);
    Protein name:
    Killer cell immunoglobulin-like receptor 2DL2;
    Alternative:
    MHC class I NK cell receptor;CD158 antigen-like family member B1;p58 natural killer cell receptor clone CL-43(p58 NK receptor CL-43);Natural killer-associated transcript 6(NKAT-6);
    CD:
    CD158b1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    348
    Sequence:
    50:
    MSLMVVSMAC | VGFFLLQGAW | PHEGVHRKPS | LLAHPGRLVK | SEETVILQCW | 
    100:
    SDVRFEHFLL | HREGKFKDTL | HLIGEHHDGV | SKANFSIGPM | MQDLAGTYRC | 
    150:
    YGSVTHSPYQ | LSAPSDPLDI | VITGLYEKPS | LSAQPGPTVL | AGESVTLSCS | 
    200:
    SRSSYDMYHL | SREGEAHECR | FSAGPKVNGT | FQADFPLGPA | THGGTYRCFG | 
    250:
    SFRDSPYEWS | NSSDPLLVSV | IGNPSNSWPS | PTEPSSKTGN | PRHLHILIGT | 
    300:
    SVVIILFILL | FFLLHRWCSN | KKNAAVMDQE | SAGNRTANSE | DSDEQDPQEV | 
    348:
    TYTQLNHCVF | TQRKITRPSQ | RPKTPPTDII | VYAELPNAES | RSKVVSCP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    UniGene:
    MIM:
    UniGene:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Killer cell immunoglobulin-like receptor 2DL2
    Cat.:
    E10474h
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Killer cell immunoglobulin-like receptor 2DL2
    Cat.:
    U10474h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Killer cell immunoglobulin-like receptor 2DL2
    Cat.:
    P10474Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Killer cell immunoglobulin-like receptor 2DL2
    Protein for Human Killer cell immunoglobulin-like receptor 2DL2

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains."
      Wagtmann N. , Biassoni R. , Cantoni C. , Verdiani S. , Malnati M.S. , Vitale M. , Bottino C. , Moretta L. , Moretta A. , Long E.O.
      Immunity2:439-449(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Natural killer cell.
    2. 2.
      "Alternatively spliced forms of human killer inhibitory receptors."
      Doehring C. , Samaridis J. , Colonna M.
      Immunogenetics44:227-230(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Highly homologous KIR genes require additional strategies to obtain complete coding sequences of KIR2DL2/3 alleles from genomic DNA."
      Hou L. , Hurley C.K. , Steiner N.K. , Belle I.
      Submitted (2008-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "Crystal structure of the HLA-Cw3 allotype-specific killer cell inhibitory receptor KIR2DL2."
      Snyder G.A. , Brooks A.G. , Sun P.D.
      Proc. Natl. Acad. Sci. U.S.A.96:3864-3869(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF 25-221;FUNCTION;DISULFIDE BONDS
    5. 5.
      "Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand."
      Boyington J.C. , Motyka S.A. , Schuck P. , Brooks A.G. , Sun P.D.
      Nature405:537-543(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 22-221 IN COMPLEX WITH HLA-CW3;DISULFIDE BONDS
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